
Vario two. | Liquid and gas analyzer
The Vario two. is the world's first mass spectrometer that can measure simultaneously from the liquid and gas phase. The liquid and gas analyzer is used in particular for fermentation monitoring and bioprocess engineering, but optimizes any processes in which parallel measurements from the liquid and gas phase are required. Simultaneous measurement from the liquid and the gas dramatically increases the benefits of mass spectrometry in relation to the acquisition costs. The combined liquid and gas measurement is patented by Variolytics and is not offered by any other supplier.
The top 4 advantages of the
Analysis Allrounder

Vario two. | Liquid and gas analyzer
You will find all the important facts, background and further information in our brochure.

Analysis all-rounder for liquid and gas measurements
With its patented inlet system, the Vario two. is designed to measure simultaneously from the liquid and gas phase. The liquid and gas analyzer is the ideal combination of a classic quadrupole mass spectrometer for gas analysis and a membrane inlet mass spectrometer (MIMS technology) for liquid analysis. As the Vario two. can be easily integrated into the industrial process, it measures continuously and without disturbing the process. The device delivers consistently accurate measurement data with low measurement noise and high linearity, allowing changes in reactions to be tracked in real time (from 25 milliseconds). The all-rounder adapts perfectly to your individual application. For example, the volatility of substances in the sample stream can be increased by changing the temperature control of the membrane module.
User-friendly hardware
and software
The membrane inlets of the device enable online and inline measurements directly in the process, so that no sample preparation is necessary. This saves time and resources and makes it possible to react quickly to changes in the process and thus optimize it. The user-friendly software architecture simplifies real-time control of the device and visualizes the measurement data in the same user interface. The hardware has a modular design - the membrane module can be replaced and autoclaved, for example, in a single step.

The ideal inlet for your measuring task
The membrane inlets from Variolytics enable stable multi-parameter measurements from the liquid. The membrane module contains a hydrophobic and organophobic membrane. At the interface of the membrane, volatile components present in the liquid are continuously transferred through the membrane into a vacuum. These parameters are then measured directly in the mass spectrometer. The membrane inlets are easy to autoclave and can be easily replaced if necessary.
Not sure which is the ideal inlet for your measurement task? Simply contact us and we will be happy to advise you.
Flow cell
Processes can be tracked online with the flow cell. For this purpose, a bypass is installed from the reaction site to the flow cell. For this reason, no probes or other components need to be inserted directly into the process. This means that the process is not disturbed by the measurements. In addition, the module enables the measurement to be influenced in a targeted manner, for example by setting a specific temperature or adding substances (e.g. acid to lower the pH).
In-situ sensor
The in-situ sensor measures directly in the process, at the reaction site, and does not require a bypass. For this reason, the in-situ probe has faster response times than the flow cell and therefore there is no time delay in the measurement. Processes in which very rapid changes occur can therefore be measured in real time. This membrane inlet is particularly suitable for measuring dissolved gas concentrations.


Ideal for multiplexing
... to measure from several sources simultaneously
Multiplexing allows customers to run several measurements on the same measuring device. This allows different samples to be analyzed simultaneously. This saves time during measurement tasks and reduces costs for expensive measurement technology. The Vario two. can also be easily integrated into a control system using our software. In biotechnology, two or even four bioreactors can be monitored and controlled simultaneously.
Latest software architecture
... for problem-free process integration
Tired of outdated software? So are we! The Vario two. offers a software architecture that can be easily integrated into process control systems or other hardware via standard interfaces. A modern user interface and smart functions make it easy to use. Automated rotators enable "stand-alone" operation for continuous measurements.





